A Deep Dive into the New PicoSure Pro: How Does It Differ from the Classic Model and Other Pico Lasers?
- นพ. กฤษณ์ บูรณโยชน์กุล
- 1 day ago
- 12 min read
PicoSure Pro is the first and only 755nm Picosecond Laser technology globally cleared by the US FDA. It effectively treats stubborn pigmentary conditions, including Melasma, Nevus of Ota, and Hori’s Macules, while minimizing the risk of Post-Inflammatory Hyperpigmentation (PIH).
This article explores the scientific and medical differences between the new PicoSure Pro and the classic PicoSure, highlighting why the 755nm Alexandrite technology outperforms other Pico Lasers for Asian skin types.
Table of Contents
How does the new PicoSure Pro differ from the classic PicoSure?
Comparison Table: How does the new PicoSure Pro differ from the classic PicoSure?
Key advantages of PicoSure Pro over other Pico lasers in Thailand
In-Depth Comparison Table: PicoSure Pro vs Pico Nd:YAG Laser
Why did Kritthada Clinic upgrade from PicoSure to the latest PicoSure Pro?
Frequently Asked Questions (FAQs): In-depth comparison between PicoSure Pro and the classic model
Conclusion: Elevate your skin with PicoSure Pro at Kritthada Clinic Bangna
How Does the New PicoSure Pro Differ from the Classic PicoSure?
The PicoSure Pro is the latest upgrade from Cynosure (USA). While it retains its signature 755nm wavelength, the machine's specifications have been enhanced for greater power and precision:
Platinum Focus™ Lens Array: This upgraded lens creates Laser-Induced Optical Breakdowns (LIOBs) more efficiently. It stimulates new collagen and elastin production, tightening pores and smoothing fine lines and acne scars with virtually no downtime.
Adjustable Fluence: The Pro model allows doctors to adjust energy levels flexibly while maintaining the same spot size, enabling highly customized treatments for different pigment depths and types.
Turbo Mode: This new mode delivers faster and stronger energy, making it ideal for treating stubborn tattoos and deep-seated, resistant pigmentation.
Expanded US FDA Clearances: It is the only Picosecond Laser officially FDA-cleared to treat Melasma, Nevus of Ota, and Hori’s Nevus safely and effectively.
Picosure Pro มีอะไรใหม่?
Comparison Table: How Does the New PicoSure Pro Differ from the Classic PicoSure?
Key Features | PicoSure Pro (Newest Model) | PicoSure (Classic Model) |
US-FDA Clearance | The only Pico device with US-FDA clearance specifically indicating treatment results for Melasma, Nevus of Ota, and Hori's Nevus. | Cleared for general pigmentation, tattoos, and skin revitalization. |
Skin Revitalization Lens | Platinum Focus™ Lens delivers up to 40% more energy (increased from 80,000 to 120,000 shots), better stimulating collagen production. | Standard Focus™ Lens Array. |
Power & Special Modes | Features Turbo Mode and more precise Fluence adjustments. Noticeably increased Peak Power. | Lower power; lacks Turbo Mode. |
Laser Handpiece | Added a 5 mm handpiece, allowing better treatment customization for various lesion sizes. | More limited handpiece sizes. |
Time to See Results | Shatters pigment more finely, resulting in fewer overall treatment sessions required. | Requires slightly more treatment sessions. |
Key Advantages of PicoSure Pro Over Other Pico Lasers in Thailand
In Thailand, popular Pico lasers are generally divided into two main categories based on their wavelength: the 755nm group (PicoSure Pro) and the 1064nm group (such as PicoWay and Discovery Pico). The significant medical differences are as follows:
755nm Wavelength: Ultimate Pigment Specificity Without Damaging Blood Vessels
PicoSure Pro utilizes the 755nm (Alexandrite) wavelength. Its standout feature, supported by research, is that the 755nm wavelength has a higher melanin absorption rate and a lower red blood cell (hemoglobin) absorption rate compared to the 1064nm wavelength.
This means the energy directly targets and destroys only the "melasma and freckle pigments" without rupturing the underlying blood vessels. As a result, after a PicoSure Pro treatment, there is typically "no pinpoint bleeding" (No Purpura), unlike 1064nm machines, which often leave bruised, red bleeding spots under the skin that require a longer recovery time.
Photoacoustic Energy (Shockwaves, Not Heat)
Post-Inflammatory Hyperpigmentation (PIH) is usually caused by accumulated heat. PicoSure Pro stands out with its PressureWave™ technology, which operates in trillionths of a second to create mechanical shockwaves (Photoacoustic energy). This crushes the pigment into tiny, sand-like particles, making it easier for the body to eliminate them with virtually no heat accumulation that could burn the skin.
Stimulating Collagen for Acne Scars with LIOBs (No Skin Peeling)
Using the special Platinum Focus™ Lens, the machine concentrates light energy into tiny points beneath the skin, creating LIOBs (Laser-Induced Optical Breakdowns) or tiny vacuoles in the epidermis. This tricks the body into accelerating the production of new collagen and elastin to repair acne scars, wrinkles, and enlarged pores—without causing open wounds or severe scabbing on the skin's surface.
The Key: The Absorption Rate of "Pigment" vs. "Blood"
The 755 nm wavelength of PicoSure Pro is highly specific to melanin and absorbs pigment up to 3 times better than blood when compared to the 1064 nm wavelength.
Pico 1064 nm (Nd:YAG): Often affects the blood vessels under the skin, leading to pinpoint bleeding or red bruises (Purpura) after the treatment, which requires patients to take several days of recovery time.
PicoSure Pro 755 nm (Alexandrite): Primarily targets melanin without destroying the surrounding blood vessels (50X more likely to absorb pigment vs. blood). This leaves the face without bruising or pinpoint bleeding post-treatment (virtually no downtime) and significantly reduces the risk of Post-Inflammatory Hyperpigmentation (PIH).
In-Depth Comparison Table: PicoSure Pro vs Pico Nd:YAG Laser
Clinical Features | PicoSure Pro (Kritthada Clinic) | General Pico Laser (1064nm / 532nm) |
Laser Medium | Alexandrite Laser (755 nm) | Nd:YAG Laser (1064 nm / 532 nm) |
Melanin Specificity | Very High (Absorbs pigment 3 times better than blood when compared to 1064nm) | Moderate (Often targets blood vessels as well) |
Post-Treatment Side Effects (Downtime) | No pinpoint bleeding; may have slight redness that fades within a few hours | Pinpoint bleeding under the skin (Purpura) is common; requires 3-7 days of downtime |
Risk of Post-Inflammatory Hyperpigmentation (PIH) | Very Low; safe for Asian skin | Higher risk if inappropriate energy levels are used for the skin type |
Special Collagen-Stimulating Lens | Proprietary Platinum Focus™ Lens Array | MLA (Micro Lens Array) or DOE |
Key Highlights (Best For) | Treating melasma, deep freckles (Hori's nevus), skin brightening, and pores with no downtime | Black/dark red tattoos, deep acne scars (for patients who can tolerate downtime) |
Global Research and Medical References
PicoSure Pro is more than just marketing hype; it is the only Picosecond Laser in the world officially cleared by the US-FDA for the treatment of three difficult-to-treat pigmentary disorders:
Melasma
Nevus of Ota
Hori’s Macules
Safety for Asian Skin (Reduced PIH Risk): A retrospective study on Asian patients published in Lasers in Surgery and Medicine found that the 755 nm Picosecond Laser excellently eliminates pigmentary disorders (such as Nevus of Ota) with a significantly lower rate of Post-Inflammatory Hyperpigmentation (PIH) compared to traditional Q-Switched lasers.
LIOBs Innovation Without Damaging the Upper Skin Layer: The Platinum Focus Lens Array delivers Picosecond energy that creates a photomechanical effect (shockwaves), shattering pigment into fine, sand-like dust without causing excessive thermal damage. This mechanism not only destroys pigment but also triggers cell signaling to produce new collagen in the dermis, leaving the outer epidermis completely unharmed.
Why Did Kritthada Clinic Upgrade from PicoSure to the Latest PicoSure Pro?
Although the original PicoSure model was a highly standard and widely accepted technology, at Kritthada Clinic Bangna, we never stop seeking the very best for our patients' treatment outcomes. This is why we decided to upgrade to the latest generation PicoSure Pro as soon as it arrived in Thailand, making us one of the first clinics to adopt it. We did this for 4 main reasons:
Unlocking Performance with the Platinum Focus™ Lens: The Pro model features a specialized lens that can deliver up to 40% more energy (increasing from 80,000 to 120,000 shots). This stimulates collagen and elastin production deeper and more densely beneath the skin, resulting in faster and more noticeable improvements in acne scars, wrinkles, and overall skin rejuvenation.
Covering Stubborn Pigmentation (US-FDA Cleared): PicoSure Pro is the only device officially cleared by the US-FDA to significantly treat complex skin issues like Melasma, Nevus of Ota, and Hori's Nevus. This surpasses the older model, which was only cleared for general pigmentation and tattoo removal.
High-Power Yet Safe Turbo Mode: The new machine features adjustable Peak Power and a Turbo Mode. This allows doctors to finely and accurately customize treatments based on each patient's specific skin condition and lesions. Pigments are shattered more finely without bruising the skin.
Less Pain, Shorter Downtime: With more stable and precise energy delivery, heat accumulation under the skin is minimized. Patients feel much more comfortable during treatment, and post-treatment redness fades faster. This perfectly suits the lifestyle of those who want clear results without the long recovery time.
Upgrading to the PicoSure Pro reaffirms Kritthada Clinic's commitment to delivering a skincare experience that is safe, modern, and provides the most worthwhile results in every single treatment.
Why Does Kritthada Clinic Choose PicoSure Pro? A Deep Dive into the Art of Combination Laser & Energy-Based Devices (EBDs)
Individual skin problems are highly complex and rarely stem from a single cause (Multi-layered Skin Concerns). For example, a patient might simultaneously struggle with deep melasma, wrinkles, acne scars, and skin laxity. Relying on just a single type of laser may not yield the perfect result.
This is the key reason why Kritthada Clinic has chosen PicoSure Pro as the "core" of our treatments, seamlessly integrating it with our clinic's signature expertise: designing Combination Laser Treatments alongside advanced Energy-Based Devices (EBDs).
1. PicoSure Pro: The Crucial Puzzle Piece that Perfectly Connects EBDs
When combining treatments with other medical equipment (Energy-Based Devices), it is absolutely essential to consider "heat accumulation under the skin" to prevent Post-Inflammatory Hyperpigmentation (PIH).
Thanks to PicoSure Pro’s 755nm technology, which primarily utilizes shockwaves (Photoacoustic energy) to destroy pigment instead of the high heat used by older lasers, the skin does not suffer from severe inflammation.
This distinct advantage allows doctors to safely and effectively use PicoSure Pro in Combination Treatments alongside skin-lifting devices or skin rejuvenation injectables (Skin Boosters) in the same session or within a close timeframe.
2. Signature Combination Treatments at Kritthada Clinic
At Kritthada Clinic, we believe that complex skin problems require comprehensive care. Utilizing PicoSure Pro—which delivers gentle photoacoustic energy with minimal heat accumulation—enables us to safely and effectively design Combination Treatments with other EBDs and Skin Boosters. Here are the 7 popular signature programs at our clinic:
PicoSure Pro Signature Combination Treatments
Program | Suitable Skin Conditions / Indications | Expected Results from Combined Innovations |
Chronic acne redness, facial spider veins (Rosacea), dull and uneven skin tone, patients looking to clear both pigmentation and blood vessels. | PicoSure Pro shatters deeply embedded pigmentation while Derma V effectively eliminates redness and capillary vessels. The result is brighter, more even-toned skin, reduced skin flushing, and excellent reduction of skin inflammation. | |
Deep melasma, Hori's nevus, stubborn dark spots, patients with multi-level complex pigmentation issues. | Elevates pigment destruction to the next level by utilizing PicoSure Pro (755nm)—which has the highest pigment absorption rate—alongside 1064/532nm wavelengths to reach pigment at all skin depths. The result is a clear reduction in stubborn dark spots, melasma, and freckles with fewer overall treatment sessions. | |
Rough skin texture, enlarged pores, poorly nourished skin, those desiring a Korean-style dewy "Glass Skin" look. | PicoSure Pro stimulates subsurface collagen while LaseMD (1927nm) gently opens micro-channels in the upper epidermis to deliver concentrated vitamins and nutrients deep into the skin. The result is smoother skin texture, minimized pores, and deeply hydrated, glowing, and plump skin. | |
4. PicoSure Pro + Frac3 Fotona (Acne & Pigment Clear) | Recurrent inflammatory acne, acne marks (PIH/PIE), oily skin, enlarged pores caused by clogged acne. | PicoSure Pro fades acne marks, while Frac3 (Fotona) delivers energy to kill C. acnes bacteria, reduce inflammation, and regulate sebaceous gland activity. The result is faster-drying acne, reduced oiliness, and a noticeable reduction in acne scars. |
5. PicoSure Pro + Microneedle RF (Total Scar & Lifting) | Deep acne scars (Ice Pick, Boxcar), severe fibrous bands (tethers), sagging skin, lack of structural firmness. | PicoSure Pro smooths the upper skin layer, while Microneedle RF delivers radiofrequency energy deep into the skin to cut through fibrous bands and stimulate deep dermal collagen and elastin production. The result is a significant lifting of acne scars and firmer, lifted facial skin. |
Mild to moderate acne scars, prematurely aged skin, fine lines, those seeking 3D skin restructuring without extended downtime. | PicoSure Pro primes the skin and stimulates foundational collagen, after which CureJet needle-lessly delivers Juvelook (a collagen booster) deep into the skin. The result is plump, hydrated skin from within, shallower acne scars, and diminished wrinkles with virtually no needle marks or severe scabbing. | |
Sensitive skin, skin requiring urgent repair, patients wanting to minimize downtime following high-energy laser treatments. | Accelerates DNA-level skin healing. Following PicoSure Pro, applying Vitaran (PN) reduces redness and inflammation while strengthening the skin barrier. The result is exceptionally fast recovery from laser treatment, a minimized risk of Post-Inflammatory Hyperpigmentation (PIH), and long-term skin health. |
(Note: Treatment programs can be customized according to each individual's unique skin condition.)
3. Experience and Expertise in Energy-Based Devices (EBDs)
World-class equipment like the PicoSure Pro can only reach its full potential in the hands of an expert physician. At Kritthada Clinic, our doctors possess a deep understanding of laser physics and the mechanisms behind every Energy-Based Device.
We never apply "default settings" to every patient. Instead, we customize energy parameters—including fluence and pulse duration—and select the appropriate wavelength for the structure of Thai skin (Skin Types III-IV). We also carefully plan the ideal timeline between laser treatments and complementary procedures (such as botox injections) to ensure optimal results with zero side effects.
Conclusion: Choosing skin care at Kritthada Clinic is not merely selecting a PicoSure Pro treatment; it is choosing a "skin ecosystem" that integrates the pinnacle of Energy-Based Device technologies, guided by true medical expertise.
Executive Summary: What is PicoSure Pro and Why Is It Effective?
Precision Pigment Innovation: A 755nm Picosecond Laser with high efficacy in targeting melanin (melasma, freckles, dark spots) without damaging surrounding blood vessels.
US-FDA Standard: The only Pico laser globally cleared by the US-FDA for the safe treatment of melasma, Nevus of Ota, and Hori’s nevus.
Comprehensive Skin Rejuvenation: Equipped with the Platinum Focus™ Lens to stimulate subcutaneous collagen, repair acne scars, and deeply tighten pores.
No Pinpoint Bleeding (No Downtime): Delivers energy via shockwaves without heat accumulation, leaving skin unbruised post-treatment, minimizing the risk of Post-Inflammatory Hyperpigmentation (PIH), and eliminating the need for recovery time.
Frequently Asked Questions (FAQs): In-Depth Comparison Between PicoSure Pro and the Classic Model
Q: How does the PicoSure Pro differ from the classic PicoSure?
A: The most distinct differences are the "energy output" and "treatment results for melasma and freckles."
Energy and Lenses: The Pro model upgrades to the Platinum Focus™ Lens, which delivers up to 40% more energy per shot (increased to 120,000 shots), better and more deeply stimulating subcutaneous collagen.
FDA Clearances: The Pro is the only model officially US-FDA cleared specifically for treating "melasma, Nevus of Ota, and Hori's macules," whereas the older model focuses on general pigmentation and tattoos.
Energy System: The Pro features Turbo Mode, allowing doctors to adjust energy with greater precision, resulting in finer pigment shattering.
Q: If I had poor results with the older PicoSure model, will switching to the Pro model be better?
A: There is a strong chance of seeing noticeably better results. With higher peak power and the Turbo Mode, the PicoSure Pro can tackle stubborn or deep-seated pigmentation that older machines might not reach or lack the power to treat. Additionally, at Kritthada Clinic, we utilize Combination Treatments alongside other lasers to comprehensively address the root cause of skin issues.
Q: Is the PicoSure Pro more painful than the older model?
A: Although the energy is higher, the delivery via a Photoacoustic shockwave lasting mere trillionths of a second generates very little heat accumulation beneath the skin. Consequently, the sensation during treatment is not more painful than the older model. Most patients feel comfortable, and we always apply numbing cream beforehand to ensure maximum relaxation.
Q: Will my skin be damaged, thinned, or severely bruised compared to the older model?
A: Not at all. A standout feature of the 755nm wavelength in both models is that the energy is not absorbed by blood vessels, resulting in "no pinpoint bleeding" (No Purpura). Post-treatment, the face will only exhibit a mild, pinkish flush that allows you to return to daily life and wear makeup normally within 1 to 2 days, with no worries about thinning skin or severe bruising.
Q: If I get treated at Kritthada Clinic, how can I be sure it’s an authentic PicoSure Pro?
A: Kritthada Clinic at Little Walk Bangna uses authentic PicoSure Pro devices imported directly from Cynosure, USA. Patients can verify our clinic's name on the official distributor's website in Thailand. Furthermore, we have earned recognition awards as one of the top providers of PicoSure Pro treatments nationwide.
Conclusion: Elevate Your Skin with PicoSure Pro at Kritthada Clinic Bangna
Choosing the right laser device is the starting point for healthy skin. If you are seeking the ultimate technology to treat melasma, freckles, dark spots, and acne scars, the PicoSure Pro is the most effective solution today, offering upgraded power, greater precision, and safety for Asian skin without leaving bruises or pinpoint bleeding post-treatment.
At Kritthada Clinic, located at the Little Walk Bangna project, we not only provide genuine, US-FDA-approved PicoSure Pro treatments, but we also excel in the art of Combination Treatment design. We analyze and customize laser energy to match each individual's skin structure, merging it with other world-class innovations to ensure clear, rapid, and worthwhile results.
Consult our experts and get a skin assessment. Do not let skin concerns undermine your confidence—let the medical team at Kritthada Clinic take care of you. Our clinic is conveniently located right on Bangna-Trat Road (Little Walk Bangna project) with ample parking space to accommodate all visitors.
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